Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. : LAI

Publications

Yu Mingcan, Li Guangjin, Lee Won-Woo, Yuan Ming, Cui Dapeng, Weyand Cornelia M, Goronzy Jörg J. Proc. Natl. Acad. Sci. U.S.A. 2012 4;109:E879-88

Pubmed

The relationship of cytomegalovirus (CMV) infection with circulatory IFN-α levels and IL-7 receptor α expression on CD8+ T cells in human aging. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity.

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Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age.

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