Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis
Bonah Kim, Hee Young Kim, Bo Ruem Yoon, Jina Yeo, Ji In Jung, Kyung-Sang Yu, Hyeon Chang Kim, Su-Jin Yoo, Jin Kyun Park, Seong Wook Kang, Won-Woo Lee. Science Signaling 2022;15:eabi7400. PUBMED Link
Induction of Unique STAT Heterodimers by IL-21 Provokes IL-1RI Expression on CD8+ T Cells, Resulting in Enhanced IL-1β Dependent Effector Function.
Dong Hyun Kim, Hee Young Kim, Won-Woo Lee. Immune Network 2021;21:e33.PUBMED Link
Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse.
Kim Bonah, Kim Hee Young, Lee Won-Woo. Front Immunol 2021; 12:687367.Pubmed
Regulatory Role of Zinc in Immune Cell Signaling
Bonah Kim and Won-Woo Lee. Molecules and Cells 2021;0Pubmed
Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells.
Kim Dong Hyun, Kim Hee Young, Cho Sunjung, Yoo Su-Jin, Kim Won-Ju, Yeon Hye Ran, Choi Kyungho, Choi Je-Min, Kang Seong Wook, Lee Won-Woo. Elife 2021;10.Pubmed
Activated Platelets Convert CD14+CD16- Into CD14+CD16+ Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization.
Lee Su Jeong, Yoon Bo Ruem, Kim Hee Young, Yoo Su-Jin, Kang Seong Wook, Lee Won-Woo. Front Immunol 2021;11:611133Pubmed
Indoxyl Sulfate-Mediated Metabolic Alteration of Transcriptome Signatures in Monocytes of Patients with End-Stage Renal Disease (ESRD).
Kim Hee Young, Lee Su Jeong, Hwang Yuri, Lee Ga Hye, Yoon Chae Eun, Kim Hyeon Chang, Yoo Tae-Hyun, Lee Won-Woo. Toxins (Basel) 2020 09;12Pubmed
Human Cytomegalovirus (HCMV)-infected Astrocytoma Cells Impair the Function of HCMV-specific Cytotoxic T Cells.
Kim Jiyeon, Lee Won Woo, Hwang Eung Soo. J Korean Med Sci 2020 7;35:e218Pubmed
Validation of CDr15 as a new dye for detecting neutrophil extracellular trap.
Kim Sang-Jin, Kim Jiyoung, Kim Bonah, Lee Won-Woo, Liu Xiao, Chang Young-Tae, Park Jong-Wan. Biochem Biophys Res Commun 2020 06;527:646-653Pubmed
Immunosenescent characteristics of T cells in young patients following haploidentical haematopoietic stem cell transplantation from parental donors.
Lee Ga Hye, Hong Kyung Taek, Choi Jung Yoon, Shin Hee Young, Lee Won-Woo, Kang Hyoung Jin. Clin Transl Immunology 2020 4;9:e1124Pubmed